Goals were scored by Sergio Ramos (3, 29), Anssumane Fati (32) and Ferran Torres (84), Ukrinform reports.
Another League A Group 4 match between Switzerland and Germany ended in a 1-1 draw.
Spain collected four points after two rounds, Ukraine has three points, Germany – two points, and Switzerland – one point.
Ukraine will play its next Nations League match against Germany in Kyiv on October 10.
Switzerland will take on Spain in Basel.
Let’s get started read our news at facebook messenger > > > Click here for subscribe