Kharkiv Mayor Ihor Terekhov broke the news on Telegram, Ukrinform reports.
"At 4:25, Kharkiv's Industrial district was shelled. Two hits by S-300 missiles," the mayor wrote.
According to Terekhov, rescue teams are working at the scene of the strikes.
"Their tentative report suggests there are no casualties," Terekhov added.
As reported, on the night of July 26, Russian troops shelled an area close to downtown Kharkiv.